The rankings, published by The Times, show the performances of every secondary school in Scotland based on the number of pupils achieving five or more Highers.
Mearns Castle, St Ninian’s and Williamwood, are all in the top 10 schools with over 70 per cent of pupils making the ‘gold standard’ of five pass grades at Higher.
Mearns Castle High School took second place, with 74 per cent of pupils achieving five Highers; followed by St Ninian’s High School in fourth place on 73 per cent.
Williamwood High also makes the top 10, in ninth place, on 70 per cent.
Eastwood High (13th, 65 per cent) and Woodfarm High (17th, 61 per cent) make the top 20 in Scotland.
Councillor Paul O’Kane, Convener for Education and Equalities at East Renfrewshire Council, said: “Each year our schools deliver outstanding exam results and it is testament to the hard work of all our pupils, staff and parents.
“Our focus is on providing pupils with a wide range of opportunities which supports them to reach their potential, and this break down of the results highlights that our approach to education is clearly having the desired impact, when compared to other schools across the country.
“To have two out of the top five performing secondary schools in Scotland, in St Ninian’s and Mearns Castle, is a fantastic achievement.
“We also have Williamwood in the top 10, Eastwood and Woodfarm in the top 20 and St Luke’s in the top 40.
“It’s also extremely pleasing to see the rise of Barrhead High from mid-table to the top 100 with a 10 per cent increase in the number of pupils gaining five Highers.
“The ethos instilled across the area is about providing pupils with a range of excellent experiences, and it’s clear that broadening pupils’ horizons with such a wide range of extra-curricular activities also supports them to excel in their academic studies.
“In addition, our targeted approach to closing the attainment gap is also reaping benefits and we are seeing continuous, year on year improvements in this area.”
Jordanhill School, Scotland’s only government-aided secondary school, topped the leaderboard for the fifth year in a row.