Officers acting under warrant entered and searched a property in Westmoreland Street, Govanhill, at around 1.35pm.
There they uncovered a major haul of what’s believed to be cannabis, said to have an estimated street value of £360,000.
Two men, aged 26, have been arrested and are in police custody in connection with the seizure.
A report will be submitted to the Procurator Fiscal.
It is expected that two men will appear at Glasgow Sheriff Court on Monday.