The trailer introduces Percival Graves - played by Colin Farrell - who can be heard addressing Eddie Redmayne’s Newt Scamander.
“Just like your suitcase, I think there’s much more to you than meets the eye,” he says, as a creature appears to start prising open the catch of the bag.
The film will bring to life J. K Rowling’s 2001 book, which was itself a spin-off from the Harry Potter series, purporting to be a textbook issued to students at Hogwarts.
Oscar-winner Redmayne plays Newt Scamander, author of the textbook.
The film is due to be released in the UK on November 18 this year.