The event has been organised by Constable Alan Mulholland, from Kildrum, who has already helped raise more than £5500 for the charity after joining 100 female motorcyclists on a trip around Scotland, dubbed the Breast Way Round.
The Community Safety Officer is hoping a further £1000 can be raised for the charity at the Cumbernauld fundraiser.
As well as the musical performances, the night will feature an auction packed with great items, such as a flat screen TV and a signed Franz Ferdinand guitar.
Proceedings kick-off at 7.30pm at the Royal British Legion club, South Muirhead Road, and all are welcome to come along and support a great cause.
Money raised will be used by Macmillan to support people in the Cumbernauld area who are living with cancer.